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Index > Protein center > Mr1(Gene name) > Rat
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  • Mr1 (Gene name),
  • Major histocompatibility complex class I-related gene protein (Protein name ),  HMR1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Mr1(Hlals);
    Protein name:
    Major histocompatibility complex class I-related gene protein;
    Alternative:
    MHC class I-related gene protein;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Heterodimerizes with B2M, this interaction is required for surface expression. Associated with the peptide-loading complex, TAPBP, CALR and PDIA3.
    Function:
    Has antigen presentation function. Involved in the development and expansion of a small population of T cells expressing an invariant T cell receptor alpha chain called mucosal-associated invariant T cells (MAIT). MAIT cells are preferentially located in the gut lamina propria and therfore may be involed in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent.
    Subcellular Location:
    Cell membrane Single-pass membrane protein Extracellular side Endoplasmic reticulum
    Protein Attributes:
    Sequence length:
    343
    Sequence:
    50:
    MMFLLPFLTV | FLAKQSHTRT | HSLRYFRLAI | SDPGPGVPEF | ISVGYVDSHP | 
    100:
    ITTYDSVTRQ | KEPRAPWMAE | NLAPDHWERY | TQLLRGWQRT | FQTELRHLQR | 
    150:
    HYNHSGLHTY | QRMIGCELLE | DGSTTGFLQY | AYDGQDFIVF | DKDTLSWLAM | 
    200:
    DNVAHITKRA | WEANLHELQY | QKNWLEEECI | AWLKRFLEYG | SDALERTEHP | 
    250:
    VVRTTRKETF | PGITTLFCRA | HGFYPPEISM | IWKKNGEEIV | QEVDYGGVLP | 
    300:
    SGDGTYQMWV | SVDLDPQTKD | IYSCHVEHCG | LQMVLEAPQE | SGNTLLVANT | 
    343:
    ISGTIILIIV | LAGVGALIWR | RRSREPKEVM | YQPTQVNEGS | SPS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Major histocompatibility complex class I-related gene protein
    Cat.:
    E0910h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Rat Major histocompatibility complex class I-related gene protein
    Cat.:
    E0910m
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Rat Major histocompatibility complex class I-related gene protein
    Cat.:
    E0910r
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat Major histocompatibility complex class I-related gene protein
    Cat.:
    E0910b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Major histocompatibility complex class I-related gene protein
    Cat.:
    U0910h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Major histocompatibility complex class I-related gene protein
    Cat.:
    U0910b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Major histocompatibility complex class I-related gene protein
    Cat.:
    U0910r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Major histocompatibility complex class I-related gene protein
    Cat.:
    U0910m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Major histocompatibility complex class I-related gene protein
    Polyclonal Antibody for Rat Major histocompatibility complex class I-related gene protein
    Cat.:
    P0910Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Major histocompatibility complex class I-related gene protein
    Cat.:
    P0910Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Major histocompatibility complex class I-related gene protein
    Cat.:
    P0910Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Major histocompatibility complex class I-related gene protein
    Monoclonal Antibody for Rat Major histocompatibility complex class I-related gene protein
    Monoclonal Antibody for Rat Major histocompatibility complex class I-related gene protein
    Monoclonal Antibody for Rat Major histocompatibility complex class I-related gene protein
    Protein for Rat Major histocompatibility complex class I-related gene protein
    Protein for Rat Major histocompatibility complex class I-related gene protein
    Protein for Rat Major histocompatibility complex class I-related gene protein
    Protein for Rat Major histocompatibility complex class I-related gene protein

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    References
    1. 1.
      "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Gibbs R.A. , Weinstock G.M. , Metzker M.L. , Muzny D.M. , Sodergren E.J. , Scherer S. , Scott G. , Steffen D. , Worley K.C. , Burch P.E. , Okwuonu G. , Hines S. , Lewis L. , Deramo C. , Delgado O. , Dugan-Rocha S. , Miner G. , Morgan M. , more...
      Nature428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Brown Norway.
    2. 2.
      "Isolation and molecular characterization of the rat MR1 homologue, a non-MHC-linked class I-related gene."
      Walter L. , Guenther E.
      Immunogenetics47:477-482(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 25-342;TISSUE SPECIFICITY
      strain: Lewis.1W.
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